Posso te seguir? proposta de um modelo de mensuração do relacionamento entre marcas de redes sociais e seus usuários: Revista Brasileira de Marketing

Objetivo: O objetivo desse estudo foi examinar a relação entre emoções, percepção de risco, valor percebido e lealdade à marca durante uma crise global para entender como as emoções incidentais, ou seja, emoções não relacionadas à decisão, podem influenciar as percepções do consumidor sobre valor de bens e lealdade à marca. Metodologia/abordagem: Usando dados coletados de 290 brasileiros durante a pandemia da Covid-19, um modelo estrutural baseado na percepção de risco, emoções positivas e negativas, valor percebido e lealdade à marca foi proposto e testado empiricamente. Originalidade/valor: Esta pesquisa confirma que emoções incidentais podem impactar o valor percebido. Sendo assim, a pesquisa aumenta a compreensão do papel das emoções na relação consumidor-produto-marca. Em segundo lugar, o estudo faz uma contribuição metodológica ao analisar as relações entre percepção de crise, emoções positivas e negativas, valor percebido e lealdade à marca em uma situação real. Vale ressaltar que estudos sobre emoções incidentais no comportamento do consumidor são geralmente induzidos por experimentos. Resultados: Os resultados mostraram que os respondentes se sentiram alertas e atentos, e estas emoções desempenharam uma função significante na relação entre emoções e valor percebido durante a pandemia. Observou-se que a percepção de risco influencia as emoções negativas e positivas, mas não influencia diretamente a lealdade à marca. Contribuição teórica e prática: Os resultados fornecem suporte para o modelo, onde as emoções incidentais influenciam o valor percebido. Sendo assim, o estudo contribuiu para a literatura examinando e confirmando a relação entre emoções incidentais e valor percebido. No entanto, a percepção de risco e as emoções não influenciam diretamente a lealdade à marca. Desenvolver produtos e serviços que resolvam os problemas oriundos das emoções vivenciadas durante uma crise podem despertar o interesse do consumidor. Como contribuição social, a pesquisa apresenta que bens e serviços podem auxiliar na regulação emocional.

SARS-CoV-2 Spike protein induces TLR4-mediated long-term cognitive dysfunction recapitulating post-COVID-19 syndrome in mice.

Cognitive dysfunction is often reported in patients with post-coronavirus disease 2019 (COVID-19) syndrome, but its underlying mechanisms are not completely understood. Evidence suggests that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Spike protein or its fragments are released from cells during infection, reaching different tissues, including the CNS, irrespective of the presence of the viral RNA. Here, we demonstrate that brain infusion of Spike protein in mice has a late impact on cognitive function, recapitulating post-COVID-19 syndrome. We also show that neuroinflammation and hippocampal microgliosis mediate Spike-induced memory dysfunction via complement-dependent engulfment of synapses. Genetic or pharmacological blockage of Toll-like receptor 4 (TLR4) signaling protects animals against synapse elimination and memory dysfunction induced by Spike brain infusion. Accordingly, in a cohort of 86 patients who recovered from mild COVID-19, the genotype GG TLR4-2604G>A (rs10759931) is associated with poor cognitive outcome. These results identify TLR4 as a key target to investigate the long-term cognitive dysfunction after COVID-19 infection in humans and rodents.

Comparison Between Conventional Intervention and Non-immersive Virtual Reality in the Rehabilitation of Individuals in an Inpatient Unit for the Treatment of COVID-19: A Study Protocol for a Randomized Controlled Crossover Trial.

Background: The new human coronavirus that leads to COVID-19 (coronavirus disease 2019) has spread rapidly around the world and has a high degree of lethality. In more severe cases, patients remain hospitalized for several days under treatment of the health team. Thus, it is important to develop and use technologies with the aim to strengthen conventional therapy by encouraging movement, physical activity, and improving cardiorespiratory fitness for patients. In this sense, therapies for exposure to virtual reality (VR) are promising and have been shown to be an adequate and equivalent alternative to conventional exercise programs. Aim: This is a study protocol with the aim of comparing the conventional physical therapy intervention with the use of a non-immersive VR software during COVID-19 hospitalization. Methods: Fifty patients hospitalized with confirmed diagnosis of COVID-19 will be divided in two groups under physiotherapy treatment using conventional or VR intervention: Group A: participants with COVID-19 will start the first day of the protocol with VR tasks in the morning and then in the second period, in the afternoon, will perform the conventional exercises (n = 25) and Group B: participants with COVID-19 will start the first day with conventional exercises in the morning and in the second period, in the afternoon, will perform activity with VR (n = 25). All participants will be evaluated with different motor and physiologic scales before and after the treatment to measure improvements. Conclusion: Considering the importance of benefits from physical activity during hospitalization, VR software shows promise as a potential mechanism for improving physical activity. The results of this study may provide new insights into hospital rehabilitation. Trial Registration: ClinicalTrials.gov, identifier: NCT04537858. Registered on 01 September 2020.

Serious Game Platform as a Possibility for Home-Based Telerehabilitation for Individuals With Cerebral Palsy During COVID-19 Quarantine - A Cross-Sectional Pilot Study.

INTRODUCTION: There is a need to maintain rehabilitation activities and motivate movement and physical activity during quarantine in individuals with Cerebral Palsy (CP). OBJECTIVE: This paper sets out to evaluate the feasibility and potential benefits of using computer serious game in a non-immersive virtual reality (VR) implemented and evaluated completely remotely in participants with CP for Home-Based Telerehabilitation during the quarantine period for COVID-19. METHODS: Using a cross-sectional design, a total of 44 individuals participated in this study between March and June 2020, 22 of which had CP (14 males and 8 females, mean age = 19 years, ranging between 11 and 28 years) and 22 typically developing individuals, matched by age and sex to the individuals with CP. Participants practiced a coincident timing game1 and we measured movement performance and physical activity intensity using the rating of perceived exertion Borg scale. RESULTS: All participants were able to engage with the VR therapy remotely, reported enjoying sessions, and improved performance in some practice moments. The most important result in this cross-sectional study was the significant increasing in rating of perceived exertion (through Borg scale) in both groups during practice and with CP presenting a higher rating of perceived exertion. CONCLUSION: Children with CP enjoyed participating, were able to perform at the same level as their peers on certain activities and increased both their performance and physical activity intensity when using the game, supporting the use of serious games for this group for home therapy and interactive games. CLINICAL TRIALS REGISTRATION: https://Clinicaltrials.gov, NCT04402034. Registered on May 20, 2020.

War against the COVID-19 pandemic: reflection in light of Florence Nightingale's nursing theory

ABSTRACT Objective: To reflect on the relationship and importance of the environmental theory regarding practices for promotion, prevention, and treatment of COVID-19. Methods: A theoretical-reflexive study about the COVID-19 pandemic in light of the environmental theory proposed by Florence Nightingale. Results: It is observed that the application of the theoretical foundations proposed by the environmental theory is related to the current practices used in the fight against the COVID-19 pandemic. Final Considerations: It is believed that the theoretical basis is fundamental for the critical-reflexive training of the nursing professional, for the consolidation of Nursing as a science;therefore, it could provide a foundation in nowadays battle against the pandemic. RESUMEN Objetivo: Reflexionar sobre la relación e importancia de la teoría ambientalista en lo que respecta a las prácticas para la promoción, prevención y tratamiento de la COVID-19. Métodos: Estudio teórico y reflexivo a respecto de la pandemia de la COVID-19 bajo la luz de la teoría ambientalista propuesta por Florence Nightingale. Resultados: Se observa que la aplicación de los fundamentos teóricos propuestos en la teoría ambientalista tiene relación con las prácticas actuales, utilizadas en el combate a la pandemia de la COVID-19. Consideraciones finales: Se cree que el embasamiento teórico es fundamental para la formación crítica y reflexiva del profesional de enfermería, para la consolidación de la Enfermería como ciencia;así, él puede fornecer apoyo en el combate a la pandemia en la actualidad. RESUMO Objetivo: Refletir sobre a relação e importância da teoria ambientalista no tocante às práticas para a promoção, prevenção e tratamento da COVID-19. Métodos: Estudo teórico-reflexivo a respeito da pandemia da COVID-19 sob a luz da teoria ambientalista proposta por Florence Nightingale. Resultados: Observa-se que a aplicação dos fundamentos teóricos propostos na teoria ambientalista tem relação com as práticas atuais, utilizadas no combate à pandemia da COVID-19. Considerações Finais: Acredita-se que o embasamento teórico é fundamental para a formação crítico-reflexiva do profissional de enfermagem, para a consolidação da Enfermagem como ciência;assim, ele pode fornecer alicerce no combate à pandemia na atualidade.

War against the COVID-19 pandemic: reflection in light of Florence Nightingale's nursing theory

ABSTRACT Objective: To reflect on the relationship and importance of the environmental theory regarding practices for promotion, prevention, and treatment of COVID-19. Methods: A theoretical-reflexive study about the COVID-19 pandemic in light of the environmental theory proposed by Florence Nightingale. Results: It is observed that the application of the theoretical foundations proposed by the environmental theory is related to the current practices used in the fight against the COVID-19 pandemic. Final Considerations: It is believed that the theoretical basis is fundamental for the critical-reflexive training of the nursing professional, for the consolidation of Nursing as a science;therefore, it could provide a foundation in nowadays battle against the pandemic. RESUMEN Objetivo: Reflexionar sobre la relación e importancia de la teoría ambientalista en lo que respecta a las prácticas para la promoción, prevención y tratamiento de la COVID-19. Métodos: Estudio teórico y reflexivo a respecto de la pandemia de la COVID-19 bajo la luz de la teoría ambientalista propuesta por Florence Nightingale. Resultados: Se observa que la aplicación de los fundamentos teóricos propuestos en la teoría ambientalista tiene relación con las prácticas actuales, utilizadas en el combate a la pandemia de la COVID-19. Consideraciones finales: Se cree que el embasamiento teórico es fundamental para la formación crítica y reflexiva del profesional de enfermería, para la consolidación de la Enfermería como ciencia;así, él puede fornecer apoyo en el combate a la pandemia en la actualidad. RESUMO Objetivo: Refletir sobre a relação e importância da teoria ambientalista no tocante às práticas para a promoção, prevenção e tratamento da COVID-19. Métodos: Estudo teórico-reflexivo a respeito da pandemia da COVID-19 sob a luz da teoria ambientalista proposta por Florence Nightingale. Resultados: Observa-se que a aplicação dos fundamentos teóricos propostos na teoria ambientalista tem relação com as práticas atuais, utilizadas no combate à pandemia da COVID-19. Considerações Finais: Acredita-se que o embasamento teórico é fundamental para a formação crítico-reflexiva do profissional de enfermagem, para a consolidação da Enfermagem como ciência;assim, ele pode fornecer alicerce no combate à pandemia na atualidade.

War against the COVID-19 pandemic: reflection in light of Florence Nightingale's nursing theory.

OBJECTIVE: To reflect on the relationship and importance of the environmental theory regarding practices for promotion, prevention, and treatment of COVID-19. METHODS: A theoretical-reflexive study about the COVID-19 pandemic in light of the environmental theory proposed by Florence Nightingale. RESULTS: It is observed that the application of the theoretical foundations proposed by the environmental theory is related to the current practices used in the fight against the COVID-19 pandemic. FINAL CONSIDERATIONS: It is believed that the theoretical basis is fundamental for the critical-reflexive training of the nursing professional, for the consolidation of Nursing as a science; therefore, it could provide a foundation in nowadays battle against the pandemic.